Professor Zhiyong Li
Faculty of Engineering,
School of Mech., Medical & Process Engineering
Biography
Professor Zhiyong Li is Professor in Biomedical Engineering at Queensland University of Technology (QUT). He has a BEng (1998) in Civil Engineering from Tongji University and a PhD (2004) in Biomedical Engineering from Queen Mary University of London. He was a research fellow and senior research fellow at University of Cambridge 2004-2010. He was elected Fellow of Wolfson College and conferred a MA (2009) from University of Cambridge. Zhiyong’s main research field is biomechanics and mechanobiology, with a long-term research interest in cardiovascular diseases (atherosclerosis, aneurysm, atrial affiliation). The main focus of his work has been the development of novel technologies for detection of high-risk rupture-prone plaques in patients with carotid and coronary atherosclerosis. The work involves MRI/IVUS/OCT imaging, stress analysis, material characterisation, mathematical/computational modelling and numerical methods. He has made significant contributions to understanding the biomechanics of plaque rupture, publishing over 100 papers collectively on vulnerable atheroma in leading journals, e.g. Circulation, JACC, Nat Rev Cardiol, Nat. Commun, NEJM, Stroke, ATVB, J Biomech, Ann Biomed Eng, Biomech Model Mechanobio. He was awarded an ARC Future Fellowship in 2014, and was the recipient of the 2015 Australia Vascular Biology Society Achievement and Career Development Award. PhD STUDENTS RECRUITMENT: Several ARC-funded PhD projects are available in Prof Li’s group. CSC (China Scholarship Council) applicants are also welcome. Please feel free to contact Prof Li for more details. Main research areas:- Biomechanics/Mechanobiology
- Hemodynamics
- Mathematical Modelling and Computational Simulation
- Medical Imaging
- Atherosclerosis/Aneurysm/Thrombosis/Atrial Fibrillation
- Model of Tissue Growth and Microcirculation
- Bone Growth and Scaffold Degradation
- Theoretical Biology/Mathematical Biology
Personal details
Positions
- Professor
Faculty of Engineering,
School of Mech., Medical & Process Engineering
Keywords
Biomechanics and Mechanobiology, Cardiovascular Disease, Atherosclerosis, Aneurysm, Atrial Affiliation, Mathematical Modelling, Computational Simulation, Fluid-Structure Interaction, Bone Growth and Scaffold Degradation, Medical Imaging, Medical Device
Research field
Biomedical Engineering, Mechanical Engineering, Interdisciplinary Engineering
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008
Qualifications
- PhD (Queen Mary University of London)
- MA (University of Cambridge)
Teaching
Unit Coordinator for: EGH414 Stress Analysis EGH424 Biofluids
Publications
QUT ePrints
For more publications by Zhiyong, explore their research in QUT ePrints (our digital repository).
Selected research projects
- Title
- Clinical imaging inspired point-of-care microtechnology for enhanced diagnosis and monitoring of recurrent stroke
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- 2023977
- Start year
- 2023
- Keywords
- MRFF
- Title
- CTCA-POC: CT Coronary Angiography Inspired Point-of-Care Technology for Enhanced Diagnosis and Monitoring of Coronary Artery Disease
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- 2016165
- Start year
- 2022
- Keywords
- coronary artery disease; atherosclerosis; plaque rupture; thrombus formation; cardiovascular disease prevention
- Title
- Integrin Activation by Fluid Flow Disturbance: Mechanobiology Approaches
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- DP200101970
- Start year
- 2020
- Keywords
- Title
- Mathematical Modelling of the Mechanobiology of Arterial Plaque Growth
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- DP200103492
- Start year
- 2020
- Keywords
- Title
- An Advanced Low Cost Minimally Invasive Cardiac Assist Device
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- AISRF53807
- Start year
- 2017
- Keywords
- Heart failure; Hypertension; Aortic stiffness; Cardiac assist; Aortic counterpulsation
- Title
- Imaging-based fluid-structure interaction modelling of carotid atherosclerotic plaque
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- FT140101152
- Start year
- 2015
- Keywords
- Atherosclerosis; Cardiovascular Biomechanics; Fluid-Structure Interaction
Projects listed above are funded by Australian Competitive Grants. Projects funded from other sources are not listed due to confidentiality agreements.
Supervision
Completed supervisions (Doctorate)
- Computational investigation of emboli behaviour during aortic cannulation (2022)
- Novel 3D Printed Hollow Porous Sphere (HPS) for Cell Dynamic Culture to Investigate the Effect of Hydrodynamic Force on Cell Behaviours (2022)
- Mechanics of Bacterial Interaction and Geometry Enhancement on Nanopatterned Surfaces (2021)
- Patient-Specific Computational Biomechanical Analysis of Carotid Atherosclerotic Plaques Based on MRI (2021)
- Image-Based Patient-Specific Computational Biomechanical Analysis of the Interaction between Blood Flow and Atherosclerosis (2020)
- On the Potential of Mg Micro-Wires for the Reinforcement of Collagen-Based Barrier Membrane for Ridge Augmentation: Structure Design, Dose Optimisation, and Surface Modification (2020)
- Atherosclerotic Plaque Tissue Characterization By Combining Imaging, Pathological and Mechanical Analysis (2019)
- The Interaction Between Left Ventricular Assist Devices and Intraventricular Flow: An in silico Evaluation (2019)
Supervision topics
- Develop microfluidic technologies for cardiovascular and cerebrovascular diseases
- Optical coherence tomography imaging of arterial tissue
- Develop point-of-care microfluidic technologies for cardiovascular and cerebrovascular diseases
- Image-based assessment of atherosclerotic plaque vulnerability: Towards a computational tool for early detection and prediction
- Image-based computational model to predict intracranial aneurysm rupture
- Experimental validation of a novel tricuspid valve design