
Professor Yin Xiao
Science and Engineering Faculty,Chemistry, Physics, Mechanical Engineering,
Biomedical Engineering and Medical Physics
Personal details
- Name
- Professor Yin Xiao
- Position(s)
- Professor
Science and Engineering Faculty,
Chemistry, Physics, Mechanical Engineering,
Biomedical Engineering and Medical Physics - IHBI Membership
Institute of Health Biomedical Innovation (IHBI),
IHBI Science and Engineering Projects,
IHBI Chem Physics Mech Engineering - IPTM - Discipline *
- Biochemistry and Cell Biology, Clinical Sciences, Medical Biotechnology
- Phone
- +61 7 3138 6240
- Fax
- +61 7 3138 6030
- yin.xiao@qut.edu.au
- Location
- View location details (QUT staff and student access only)
- Identifiers and profiles
-
- Qualifications
-
PhD (University of Queensland)
- Professional memberships
and associations - Australian and New Zealand Orthopaedic Research Society
- Australasian Society for Biomaterials and Tissue Engineering
- Tissue Engineering and Regenerative Medicine International Society
- Australian Society for Medical Research
- International Association for Dental Research
- International Chinese Hard Tissue Society
- Keywords
-
Biomaterials, Bone, Bone marrow stem cell, Dentistry, Osteoarthritis, Osteoblast, Stem cell, Tissue engineering
Biography
Professor Yin Xiao is a professor in Bone and Tissue Engineering at Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT). He is the Director of Australia-China Centre for Tissue Engineering and Regenerative Medicine and a group leader of the bone and clinical research program. He obtained his BDSc and MDSc from Wuhan University (Hubei Medical University), China, with more than 10 years clinical experience. In 2000, he graduated with a PhD from School of Dentistry at the University of Queensland, Australia, and worked as a research officer there for two years following his graduation. This was followed by an NHMRC Peter Doherty Fellowship at the School of Life Sciences at the QUT. In 2004 he was awarded an NHMRC Visiting Fellowship for 6 month at the Bone Tissue Engineering Centre at the University of Carnegie Mellon, PA, USA. During this period (2003–2007) he was also appointed an Honorary Research Advisor to the School of Dentistry, UQ. In 2012 he was appointed a Professor of Bone Biology and Tissue Engineering at the Department of Biomedical Engineering at QUT and has been appointed to a number of honorary senior positions in several Universities, including currently an adjunct professor at Griffith University and three Chinese universities: Wuhan University in Wuhan; Sun Yat-sen University in Guangzhou, and Fujian Medical University in Fuzhou.
Teaching
Teaching areas
- Medical Engineering
- Biomaterials
- Bone Biology.
Publications
- Chen Z, Wu C, Gu W, Klein TJ, Crawford RW, Xiao Y, (2014) Osteogenic differentiation of bone marrow MSCs by beta-tricalcium phosphate stimulating macrophages via BMP2 signalling pathway, Biomaterials p1507-1518
- Truong NP, Gu W, Prasadam I, Jia Z, Crawford RW, Xiao Y, Monteiro M, (2013) An influenza virus-inspired polymer system for the timed release of siRNA, Nature Communications p1-7
- Prasadam I, Mao X, Shi W, Crawford RW, Xiao Y, (2013) Combination of MEK-ERK inhibitor and hyaluronic acid has a synergistic effect on anti-hypertrophic and pro-chondrogenic activities in osteoarthritis treatment, Journal of Molecular Medicine p369-380
- Wu C, Zhou Y, Xu M, Han P, Chen L, Chang J, Xiao Y, (2013) Copper-containing mesoporous bioactive glass scaffolds with multifunctional properties of angiogenesis capacity, osteostimulation and antibacterial activity, Biomaterials p422-433
- Zhou Y, Wu C, Zhang X, Han P, Xiao Y, (2013) The ionic products from bredigite bioceramics induced cementogenic differentiation of periodontal ligament cells via activation of the Wnt/Beta-catenin signalling pathway, Journal of Materials Chemistry B p3380-3389
- Wu C, Zhou Y, Fan W, Han P, Chang J, Yuen J, Zhang M, Xiao Y, (2012) Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering, Biomaterials p2076-2085
- Tumkur Jaiprakash A, Prasadam I, Feng J(, Liu Y, Crawford R, Xiao Y, (2012) Phenotypic characterization of osteoarthritic osteocytes from the sclerotic zones: A possible pathological role in subchondral bone sclerosis, International Journal of Biological Sciences p406-417
- Han P, Wu C, Chang J, Xiao Y, (2012) The cementogenic differentiation of periodontal ligament cells via the activation of Wnt/Beta-catenin signalling pathway by Li+ ions released from bioactive scaffolds, Biomaterials p6370-6379
- Prasadam I, van Gennip S, Friis T, Shi W, Crawford RW, Xiao Y, (2010) ERK-1/2 and p38 in the regulation of hypertrophic changes of normal articular cartilage Chondrocytes induced by osteoarthritic subchondral osteoarthritica subchondral osteoblasts, Arthritis and Rheumatism p1349-1360
- Fan W, Crawford RW, Xiao Y, (2010) Enhancing in vivo vascularized bone formation by cobalt chloride-treated bone marrow stromal cells in a tissue engineered periosteum model, Biomaterials p3580-3589
For more publications by this staff member, visit QUT ePrints, the University's research repository.
Research projects
Grants and projects (Category 1: Australian Competitive Grants only)
- Title
- A Multiscale Modelling Framework for Mechanical Properties of ECM
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- DP150100828
- Start year
- 2015
- Keywords
- Hierarchical multiscale modelling; Mechanical behaviour; Extracellular Matrix
- Title
- Coupling an injectable gel and MSC microtissues to enhance cartilage repair
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- 1083857
- Start year
- 2015
- Keywords
- cartilage; regenerative medicine; stem cell therapy; biomedical engineering; biomaterials
- Title
- Hypoxia-mimicking Bio-scaffold for Skeleton Regeneration
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- DP120103697
- Start year
- 2012
- Keywords
- Bone Substitute; Hypoxia; Scaffolds; Regenerative Medicine
- Title
- MAPK/ERK pathway in osteoarthritis
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- 1032738
- Start year
- 2012
- Keywords
- osteoarthritis; pathogenesis; cell signalling; kinases; animal model
- Title
- Cementogenesis and New Periodontal Attachment Formation Using Cell Sheets
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- 597455
- Start year
- 2010
- Keywords
- Periodontal Disease; Tissue Regeneration; Cell Biology; Wound Healing
Supervision
Completed supervisions (Doctorate)
- Controlling whole blood activation and Resultant clot properties on various material surfaces: a possible therapeutic approach for enhancing bone healing (2013)
- Interactions between Undifferentiated and Osteogenically Differentiated Mesenchymal Stromal Cells during Osteogenesis (2013)
- The Ancient Gene C12ORF29: An Exploration of its role in the Chordate Body Plan (2013)
- Influence of Culture Conditions on the Molecular Signature of Mesenchymal Stem Cells (2011)
- Cross-talk of subchondral bone osteoblasts and articular cartilage chondrocytes: a new insight in understanding osteoarthritis pathogenesis (2010)
- Physiological Investigation of Periosteum Structure and its Application in Periosteum Tissue Engineering (2010)
- Characterisation of Mesenchymal Cells from Osteophytes in Osteoarthritis (2009)
- Characterization of Bone Marrow Stromal Clonal Populations derived from Osteoarthritis Patients (2008)