Dr Bill Lott
Faculty of Creative Industries, Education & Social Justice,
School of Communication,
Professional Communication
Biography
Research theme: Chemistry and Medical BiotechnologyResearch discipline: Chemistry, Physics and Mechanical Engineering
Research areas
Nanotechnology
Molecular Virology
The study of molecular strategies and mechanisms employed by positive-sense single-stranded RNA viruses in the family Flaviviridae.
Antiviral drug design
Hepatitis C-specific antiviral design, targeting novel interactions between the viral genomic RNA and trans-acting viral and host factors.
Temporal RNA structure and function
Elucidating the role of temporal RNA secondary structure on the timing of essential viral functions.
Personal details
Positions
- Sessional Academic (2023)
Faculty of Creative Industries, Education & Social Justice,
School of Communication,
Professional Communication
Keywords
nanotechnology, medical biotechnology, analytical chemistry, virology, stem cells, prostate cancer, Hepatitis C, Dengue, popular science, science education
Research field
Nanotechnology, Biomedical Engineering, Medicinal and Biomolecular Chemistry
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008
Qualifications
- PhD Organic Chemistry (University of Utah)
Professional memberships and associations
Teaching
Publications
- Lott, B. & Doran, M. (2013). Do RNA viruses require genome cyclisation for replication? Trends in Biochemical Sciences, 38(7), 350–355. https://eprints.qut.edu.au/60782
- Marsh, J., Lott, B., Tyndall, J. & Huston, W. (2013). Proteolytic activation of Chlamydia trachomatis HTRA is mediated by PDZ1 domain interactions with protease domain loops L3 and LC and beta strand beta 5. Cellular and Molecular Biology Letters, 18(4), 522–537. https://eprints.qut.edu.au/62665
- Babur, B., Ghanavi, P., Levett, P., Lott, B., Klein, T., Cooper-White, J., Crawford, R. & Doran, M. (2013). The interplay between chondrocyte redifferentiation pellet size and oxygen concentration. PLoS One, 8(3), 1–12. https://eprints.qut.edu.au/60682
- Kabiri Renani, M., Kul, B., Lott, W., Futrega, K., Ghanavi, P., Upton, Z. & Doran, M. (2012). 3D mesenchymal stem/stromal cell osteogenesis and autocrine signalling. Biochemical and Biophysical Research Communications, 419(2), 142–147. https://eprints.qut.edu.au/52741
- Li, D., Lott, W., Lowry, K., Jones, A., Thu, H. & Aaskov, J. (2011). Defective interfering viral particles in acute dengue infections. PLoS One, 6(4), 1–12. https://eprints.qut.edu.au/43886
- Romero, T., Tumban, E., Jun, J., Lott, W. & Hanley, K. (2006). Secondary Structure Of Dengue Virus Type 4 3 ' Untranslated Region: Impact Of Deletion And Substitution Mutations. Journal of General Virology, 87, 3291–3296. https://eprints.qut.edu.au/23189
- Li, D., Lott, W., Martyn, J., Haqshenas, G. & Gowans, E. (2004). Differential effects on the hepatitis C virus (HCV) internal ribosome entry site by vitamin B12 and the HCV core protein. Journal of Virology, 78(21), 12075–12081. https://eprints.qut.edu.au/10445
- Li, D., Takyar, S., Lott, W. & Gowans, E. (2003). Amino acids 1-20 of the hepatitis C virus (HCV) core protein specifically inhibit HCV IRES-dependent translation in HepG2 cells, and inhibit both HCV IRES- and cap-dependent translation in HuH7 and CV-1 cells. Journal of General Virology, 84(4), 815–825. https://eprints.qut.edu.au/10446
- Takyar, S., Gowans, E. & Lott, W. (2002). Vitamin B12 stalls the 80 S ribosomal complex on the hepatitis C internal ribosome entry site. Journal of Molecular Biology, 319(1), 1–8. https://eprints.qut.edu.au/10447
- Lott, W., Takyar, S., Tuppen, J., Crawford, D., Harrison, M., Sloots, T. & Gowans, E. (2001). Vitamin B12 and hepatitis C: Molecular Biology and Human Pathology. Proceedings of the National Academy of Sciences, 98(9), 4916–4921. https://eprints.qut.edu.au/10182
QUT ePrints
For more publications by Bill, explore their research in QUT ePrints (our digital repository).