Personal details

Name
Associate Professor Makrina Totsika
Position(s)
Principal Research Fellow
Faculty of Health,
School - Biomedical Sciences,
Research - Biomedical Sciences
IHBI Membership
Institute of Health Biomedical Innovation (IHBI),
IHBI Health Projects,
IHBI Biomedical Sciences - CDA
Discipline *
Medical Microbiology, Microbiology, Genetics
Phone
+61 7 3138 0410
Email
Location
View location details (QUT staff and student access only)
Identifiers and profiles
ORCID iD Twitter
Qualifications

PhD (University of Edinburgh)

Professional memberships
and associations

Fellow of the Australian Society for Microbiology (FASM), Member of the American Society for Microbiology (ASM), Member of the Australian Society for Medical Research (ASMR)

Keywords

bacterial pathogenesis, adhesins, biofilms, virulence, urinary tract infections, intestinal infections, E. coli, Salmonella, antimicrobial resistance, antivirulence therapeutics

* Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008

Biography

Dr Makrina Totsika is currently a Vice-Chancellor’s Principal Research Fellow at QUT. Originally from Volos, Greece, Makrina moved to Scotland in 1998 to study at the University of Edinburgh, where she graduated with a First Class BSc(Hons) in Biological Sciences-Genetics (2002), a MSc by Reseach in Life Sciences with Distinction (2003) and a PhD in Bacterial Genetics (2007). Makrina was the recipient of a prestigious Wellcome Trust 4-Year PhD studentship for her research project on virulence gene regulation in pathogenic bacteria that she conducted at the Centre for Infectious Diseases Research, University of Edinburgh. Makrina immigrated to Australia in 2007 as a postdoctoral researcher at the University of Queensland and then at QUT as an ARC DECRA fellow and a Vice-Chancellor’s Research Fellow. She was promoted to Associate Professor in 2018. Makrina has authored 74 scientific articles, reviews and editorials and has been awarded several grants and fellowships from the ARC, NHMRC and philanthropic foundations. Her work is at the forefront of anti-virulence drug research and development, which is promising to revolutionise the way we treat bacterial infections that are no longer treatable with antibiotics. Makrina is a frequent science communicator and winner of the 2016 Queensland Young Tall Poppy Scientist of the Year award by the Australian Institute of Policy and Science and the 2018 Frank Fenner award by the Australian Society for Microbiology. 

This information has been contributed by Associate Professor Makrina Totsika.

Teaching

Microbiology 2nd and 3rd year units – LQB362, LQB594

Infectious Diseases Capstone unit – LQB694

Honours, Masters, MPhil and PhD program

This information has been contributed by Associate Professor Makrina Totsika.

Experience

Flying Scientist – ‘Engaging Rural Queenslanders in Science’, Office of the Queensland Chief Scientist and Wonder of Science

Research Supervisor for the QUT STEM for High Schools Research Internships Program

Public Lecture, National Science Week 2014 ‘When antibiotics stop working, the bugs fight back’

QLD Finalist, Fresh Science 2012 ‘Meet the next deadly E. coli  superbug’ 

This information has been contributed by Associate Professor Makrina Totsika.

Publications


For more publications by this staff member, visit QUT ePrints, the University's research repository.

Research projects

Grants and projects (Category 1: Australian Competitive Grants only)

Title
Molecular Mechanisms of Novel Bacterial Copper Defense Proteins
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
DP190101613
Start year
2019
Keywords
Title
DsbA Foldases from Multidrug Resistant Pathogens as Targets for New Antimicrobials
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1144046
Start year
2018
Keywords
Infection, Virulence, Enzyme Inhibitors, Enzyme Activity, Antimicrobial Therapy
Title
DsbA Inhibitors: From Hits to Leads
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1099151
Start year
2016
Keywords
Title
The current multidrug resistant Escherichia coli pandemic: exploring novel therapies against the predominant culprit E. coli ST131.
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1069370
Start year
2014
Keywords
Escherichia Coli; Adhesins; Virulence; Urinary Tract Infection (UTI); Multidrug Resistance; Fimbriae; Infectious Diseases
Title
Understanding how bacteria become sticky
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
DE130101169
Start year
2013
Keywords
Bacterial Adhesins; Disulfide Bond Proteins; Periplasmic Chaperones

Supervision