Personal details

Name
Professor Damien Harkin
Position(s)
Professor
Faculty of Health,
School - Biomedical Sciences
IHBI Membership
Institute of Health Biomedical Innovation (IHBI),
IHBI Health Projects,
IHBI Biomedical Sciences - CDA
Discipline *
Optometry and Ophthalmology, Biomedical Engineering, Medical Biotechnology
Phone
+61 7 3138 6146
Fax
+61 7 3138 6030
Email
Location
View location details (QUT staff and student access only)
Identifiers and profiles
ORCID iD Twitter LinkedIn
Qualifications

Doctor of Philosophy (University of Adelaide), Master of Tertiary Education (Management) (The University of Melbourne), Graduate Certificate in Reserach Management and Policy (The University of Melbourne)

Professional memberships
and associations

Australia and New Zealand Cornea Society and Association for Research in Vision and Opthalmology

Keywords

Biomaterials, Cell therapy, Cornea, Epithelium, Histopathology, Limbus, Mesenchymal stromal cells, Retina, Stem cells, Tissue engineering

* Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008

Biography

Research theme: Health Research discipline: Medical Sciences Research program: Ocular Cell Biology  – Vision and Eye Domain, IHBI
Research areas
Development of fibroin-based materials for ocular tissue reconstruction. Fibroin is a natural protein found in silk and can be readily purified and re-modelled to create scaffolds on which to grow new patient tissue. We have successfully grown corneal cells on fibroin and are extending this work to include retinal cells.
Retinal diseases associated with ageing. One of the primary factors associated with increasing retinal disease in Australia is simply age. Our program therefore hopes to identify potential ways of reversing the ageing process within the retina through a combination of cell-based and clinical studies.
Areas of expertise:

  • Ocular surface epithelia
  • Limbal stem cells
  • Cell based therapies
  • Tissue Engineering
  • Cell culture, histology, microscopy

Current grants: IHBI Seed Grant, 2007. $64,704: A pilot study of RPE cell responses to vitronectin, IGF family proteins and hypoxia – in relation to age related maculopathy. Selected research projects:

  • Trial of cultured limbal epithelial grafts for limbal repair.
  • Development of silk protein (fibroin) based scaffolds for ocular cells.
  • Development of novel markers for stromal cells within the ocular surface.
  • Optimisation of growth factor requirements for cultured ocular cells.
  • Investigation of RPE cell responses to vitronectin, IGF family proteins and hypoxia – in relation to age related maculopathy.
This information has been contributed by Professor Damien Harkin.

Teaching

Teaching discipline: Medical Science
Teaching areas

  • Histopathology
  • Pathology
  • Anatomy & Physiology

 

This information has been contributed by Professor Damien Harkin.

Publications


For more publications by this staff member, visit QUT ePrints, the University's research repository.

Research projects

Grants and projects (Category 1: Australian Competitive Grants only)

Title
A fibroin-based prosthetic Bruch's membrane for the treatment of age-related macular degeneration
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1080302
Start year
2015
Keywords
macular degeneration; extracellular matrix; biomaterials; retinal function; regenerative medicine
Title
Development of a cultured tissue substitute to repair the ageing retina
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1074866
Start year
2014
Keywords
Title
A novel mesenchymal stromal cell and biomaterial for corneal reconstruction
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1049050
Start year
2013
Keywords
cornea replacement; stem cells; biomaterials; corneal wound healing; corneal transplantation
Title
Growing Cells on Silk Film to Replace Corneal Grafting
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
Start year
2013
Keywords
Title
Development of a novel bioengineered tissue construct for repairing the eye.
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
553038
Start year
2009
Keywords
Eye; Cornea; Limbus; Silk Protein; Electrospinning

Supervision