Personal details

Name
Associate Professor Leila Cuttle
Position(s)
Principal Research Fellow
Faculty of Health,
School - Biomedical Sciences,
Research - Biomedical Sciences
IHBI Membership
Institute of Health Biomedical Innovation (IHBI),
IHBI Health Projects,
IHBI Biomedical Sciences - IPTM
Discipline *
Medical Physiology, Medical Biochemistry and Metabolomics, Public Health and Health Services
Phone
+61 7 3069 7208
Email
Location
View location details (QUT staff and student access only)
Identifiers and profiles
ORCID iD Twitter LinkedIn
Qualifications

PhD (University of Queensland), Bachelor of Science with Honours (University of Queensland)

Professional memberships
and associations

Head of the Burns and Trauma Research Laboratory at the Centre for Children’s Health Research, Institute of Health and Biomedical Innovation (IHBI), Queensland University of Technology. Group Leader in the Centre for Children’s Burns and Trauma Research (CCBTR), a multi-disciplinary research team across several institutions.

  • Committee Member (and previous secretary 2012-2016) of the Australasian Wound and Tissue Repair Society (AWTRS), Member of the Australian and New Zealand Burn Association (ANZBA), Member of the Australian Society for Medical Research (ASMR), Member of Women in Technology (WiT).
  • Current organizing committee for the Australian and New Zealand Burn Association Annual Scientific Conference and Scientific Forum chair, Brisbane October 2018. Previously organized the Australian and New Zealand Burn Association Annual Scientific Conference in Brisbane October 2011, was chair of one of the sessions and organized and chaired the additional Scientific Forum at that conference. Current organizing committee for the Cutaneous Biology Conference and EMCR Program, North Stradbroke Island October 2018. Also previously organized the Australasian Wound and Tissue Repair Society Conference in Gold Coast 2014 and Sydney 2012 and chaired an Early Career Researcher Masterclass Session as part of that conference.
Keywords

Burns, Burn Injury, Injury Prevention, Trauma, Traumatic Injury, Child Pain, Paediatric Burns, Paediatric Wound healing, Child Health, Physical Health, Psychological Health, First aid treatment, Pre-hospital Care, Burn Treatments, Hydrogel Dressings, Wounds, Skin, Epithelium, Wound healing, Re-epithelialisation, Repair, Regeneration, Scar tissue, Scarring, Pathology, Tissue Destruction, Apoptosis, Necrosis, Tissue Culture, In Vitro Wound Models, 3D Skin Models, In Vivo Wound Models, Biomarker Discovery, Proteomics, Blister Fluid, Saliva, Clinical Trials, Patient Data

* Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008

Biography

Hi! I’m a full-time research, NHMRC Career Development  Fellow working on paediatric burns and trauma research. I work in the Institute of Health and Biomedical Innovation (IHBI) at the Centre for Children’s Health Research which is next to the Lady Cilento Children’s Hospital in South Brisbane. My research strives to improve outcomes for children with burn injuries and my work is focused in several different areas:

  1. to publicly promote awareness of first aid treatment and its benefits to the healing burn wound
  2. to determine what conditions are required for burn injuries to occur – which is important for preventing burn injuries and developing effective legislation and product safety
  3. to investigate what pathological processes occur in the skin after burns and how these could be altered in order to improve wound healing
  4. to examine the relationship between pain, stress and the wound healing response
  5. to compare currently available wound healing treatments to develop best practice and to develop new therapies which are more effective.

At IHBI, I work with the Tissue Repair and Translational Physiology Program to examine the cellular mechanisms and processes behind burn tissue pathology. Previously I have also been involved in other research projects including: fetal scarless tissue repair and development of laboratory tools and models to examine burn injury and scar formation. During my PhD, I determined the optimal first aid treatment for burn injuries. This published work was used to develop guidelines for the treatment of burns internationally and for a “Cool Burns for 20 minutes” first aid public education campaign. This treatment has been shown recently to lead to decreased requirement for skin grafting operations, decreased admission to intensive care and shorter hospital length of stay for burn patients. It is really satisfying to know that research I conducted during my PhD has lead to improvement in the lives of people who have suffered from a burn injury.

This information has been contributed by Associate Professor Leila Cuttle.

Teaching

Teaching and Supervision of Research: I am looking for new research students in 2018 and I have several different research projects available.  The main focus of my lab group is to conduct research which aims to improve the lives of children affected by burn injury through developing new therapies to enhance wound healing and reduce scarring and by understanding how burn injuries occur and how to prevent them.

  • PhD – Biomarkers of healing in burned children   Predicting how well children with burn injuries will heal is important in order to provide best treatment and reduce scarring. In this project, saliva will be collected from children at the Lady Cilento Children’s Hospital and analysed for proteins and inflammatory markers. These markers will then be related to the patient’s wound healing outcomes to identify potential biomarkers that can predict patient healing trajectories. This project will involve working in the hospital burn clinic, contact with patients and their families, mass spectrometry/proteomic techniques and ELISAs/Western blotting. Students who have an interest in the clinical applications of laboratory work and working in a hospital environment are encouraged to apply. Please contact me for more information (Leila.cuttle@qut.edu.au; 07 3069 7208).

I have several other projects currently running and would welcome students for any of these. Please email me if you would like any information on the following:

  • 3D printed skin to test new burn treatments
  • Validation of biomarkers of burn wound healing in burn blister fluid and development of point-of-care diagnostic immunoassays
  • The pathological processes that occur in skin after burn injury, burn wound progression/conversion
This information has been contributed by Associate Professor Leila Cuttle.

Experience

Links and photos of my lab and research

  • My work was recently featured on the QUT website “Real Health Matters”. A short video describing work that happens in my lab can be found here:

http://www.realhealthmatters.org.au/portfolio/leila-cuttle/

  • Want to see the kinds of stuff our lab group gets up to? For some photos check this out:

https://www.flickr.com/photos/147560381@N07/albums/72157675281358953

  • If you want to see some more information on children’s burns and trauma, our Centre for Children’s Burns and Trauma Research website is here:

http://www.ccbtr.com.au/

This information has been contributed by Associate Professor Leila Cuttle.

Publications


For more publications by this staff member, visit QUT ePrints, the University's research repository.

Awards

Awards and recognition

Type
Recipient of a Nationally Competitive Research Fellowship
Reference year
2017
Details
NHMRC Career Development Fellowship 1; APP#1130862 Better healing for children's burn injuries; 2017-2020; $425,048
Type
Academic Honours, Prestigious Awards or Prizes
Reference year
2016
Details
Australian and New Zealand Burn Association winning paper in the Scientific Forum, Annual Meeting, October 2016, Auckland
Type
Academic Honours, Prestigious Awards or Prizes
Reference year
2016
Details
Australasian Wound and Tissue Repair Society Early Career Travel Grant to attend AWTRS Conference, November 2016, Melbourne, $500
Type
Academic Honours, Prestigious Awards or Prizes
Reference year
2014
Details
Awarded a medal by the Stuart Pegg Paediatric Burns Centre, Royal Children's Hospital and Health Services District, for services to children¿s burns
Type
Academic Honours, Prestigious Awards or Prizes
Reference year
2014
Details
Awarded a medal by the University of Queensland, Department of Paediatric and Child Health, for services to the Department
Type
Advisor/Consultant for Community
Reference year
2012
Details
Asked to advise on policy regarding burn first aid treatment and hydrogel dressings by burn care advisors in London, following my presentation at the International Society of Burn Injuries conference in Scotland, September 2012.
Type
Committee Role/Editor or Chair of an Academic Conference
Reference year
2012
Details
Australasian Wound and Tissue Repair Society Conference Organising Committee and chair of ECR Masterclass session, Sydney 2012
Type
Recipient of a Nationally Competitive Research Fellowship
Reference year
2012
Details
Fellowship Type: NHMRC Principal Research Fellowship Project Title: Improving the pre-hospital treatment and acute management of burned children External Reference :1035907 Years Awarded: 2012-2015 Total Funding Awarded: $355,276
Type
Advisor/Consultant for Industry
Reference year
2011
Details
The Clinical Practice Guidelines of Queensland Ambulance Service were updated in April 2011, to change the treatment irrigation time of burn wounds from 10 to 20 minutes and to revise the recommendations regarding the use of hydrogel dressings on burn wounds, on the basis of my research.
Type
Committee Role/Editor or Chair of an Academic Conference
Reference year
2011
Details
Australian and New Zealand Burn Association Conference Scientific Organising Committee, as well as Scientific Burn/Wound Forum organiser and chair, Brisbane 2011

Research projects

Grants and projects (Category 1: Australian Competitive Grants only)

Title
Better healing for children's burn injuries
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1130862
Start year
2017
Keywords
Burn Injury; Pathology; Injury Prevention; Wound Healing; Wound Re-epithelialisation
Title
Improving the pre-hospital treatment and acute management of burned children
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1035907
Start year
2012
Keywords
burns; burn injury; wound healing; wound repair; pathology

Supervision

  • *** Are you looking for a PhD project? ***  Please see available projects listed below and email me if you would like further information.

  • I have supervised and mentored students with clinical, laboratory and public health backgrounds and love working in a multi-disciplinary team. I have supervised to completion 4 PhDs, 3 Masters (1 full time, 2 part time) and 3 Honours students (2 biomedical, 1 MBBS medical program).  I currently supervise 3 PhD students (at QUT and University of Queensland) and 2 research assistants.

  • Projects available include:

    • 3D printed skin to test new burn treatments
    • Validation of biomarkers in blister fluid and development of diagnostic assays
    • The pathological processes that occur in skin after burn injury

Current supervisions

Completed supervisions (Doctorate)