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Professor Nathan Subramaniam

Faculty of Health,
School - Biomedical Sciences

Personal

Name
Professor Nathan Subramaniam
Position(s)
IHBI Theme Leader, Chronic Disease and Ageing
Faculty of Health,
School - Biomedical Sciences
Professor in Biomedical Sciences (Molecular Medicine)
Faculty of Health,
School - Biomedical Sciences
IHBI Membership
Institute of Health Biomedical Innovation (IHBI),
IHBI Health Projects,
IHBI Biomedical Sciences - CDA
Discipline *
Clinical Sciences, Biochemistry and Cell Biology, Genetics
Phone
+61 7 3138 2980
Email
Location
View location details (QUT staff and student access only)
Identifiers and profiles
ORCID iD
Qualifications

PhD (Purdue University)

Professional memberships
and associations

Current Appointments  

  • Australian Institute of Tropical Health and Medicine (AITHM)

  Professional Memberships

  • American Society for Cell Biology (ASCB)
  • American Association for the Study of Liver Disease (AASLD)
  • American Physiological Society (APS)
  • American Society of Hematology (ASH)
  • Asia-Pacific Association for the Study of the Liver (APASL)
  • International BioIron Society (IBIS)
  • Australian and New Zealand Society for Cell and Developmental Biology Inc. (ANZSCDBI)
  • Gastroenterological Society of Australia (GESA).
Keywords

Cell Biology, Molecular Biology, Genetics, Signal Transduction, Iron Biology, Iron Disorders, Haemochromatosis, Iron Overload, Anaemia, Liver Biology, Liver Disease, Hepatic Fibrosis, Animal Models of Disease, Next-generation Sequencing, Genetic Modifiers of Disease, Functional Analysis of Variants, Celular Anaysis, Cellular Models, Non-HFE Haemochromatosis, Atypical Iron Disorders, Genetic Analysis, Non-Alcoholic Fatty Liver Disease, Liver Damage, SNARES, Golgi, Protein Trafficking, Transferrin Receptor, Ferritin, Iron proteins, Hepcidin, Ferroportin, Transferrin receptor 2, Hemojuvelin

* Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008

Biography

Prof Nathan Subramaniam received his PhD from Purdue University, W. Lafayette,Indiana,USA. He did his postgraduate research at the Department of Biochemistry, University of California at Davis, USA. He then joined the group of Prof Wanjin Hong at the Institute of Molecular and Cell Biology, Singapore, where he completed his postdoctoral training on cell biology and protein trafficking. Prof Nathan Subramaniam established his own research group, the Membrane Transport Laboratory at the Queensland Institute of Medical Research, Brisbane, Australia in 1999. He has an Honorary Professor appointment in the Faculty of Medicine and Biochemical Sciences, University of Queensland. In 2016 he was appointed a Research Capacity Building Professor as Professor in Biomedical Sciences (Molecular Medicine) at the Queensland University of Technology. He  established his research group, the Liver Disease and Iron Disorders Research Group, at the Institute of Health and Biomedical Innovation (IHBI) in August 2016. Prof Subramaniam’s interests lie in the study of liver injury and understanding how the liver regulates iron homeostasis. Prof Subramaniam has many years of experience in the research of iron overload disorders and was instrumental in defining many genetic mutations associated with the iron overload disorder hereditary haemochromatosis.  His basic science interests include defining the functional consequences of these disease-causing mutations and elucidating the molecules and mechanisms regulating iron homeostasis. His group has developed novel Next-Generation sequencing tools to examine the molecular basis of iron disorders and novel in vitro and in vivo models to investigate liver injury and iron metabolism. An important area of research in the group is the study of liver diseases associated with liver injury, co-toxicity associated increased fat and iron, and liver fibrosis.

This information has been contributed by Professor Nathan Subramaniam.

Publications

For publications by this staff member, visit QUT ePrints, the University's research repository.

Awards

Awards and recognition

Type
Recipient of a Nationally Competitive Research Fellowship
Reference year
2017
Details
NHMRC Senior Research Fellowship
Type
Recipient of a Nationally Competitive Research Fellowship
Reference year
2012
Details
NHMRC Senior Research Fellowship

Research projects

Grants and projects (Category 1: Australian Competitive Grants only)

Title
Hormone Transport by Alpha-2-Macroglobulin: Novel Roles in Regulating Hormone Activity
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1128152
Start year
2017
Keywords
Hormones; Hormone Action; Hormone Receptors; Protein Binding; Hormone Signalling
Title
Liver Injury and Iron Homeostasis in Health and Disease
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1118888
Start year
2017
Keywords
Liver Disease; Iron Metabolism; Liver Fibrosis; Erythropoiesis; Animal Model
Title
SARA: Delineating its Association with the Onset and Development of Liver Fibrosis
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1100088
Start year
2016
Keywords
Liver Injury; Signalling Pathways; Liver Fibrosis; Transforming Growth Factor Beta (TGF-beta); Animal model
Title
Delineating the Relationship between Iron and Peroxisomal Disorders: The Role of the Peroxisomal Enzyme GNPAT in Iron-Overload Disorders
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1082224
Start year
2015
Keywords
Haemochromatosis; Iron Metabolism; Peroxisomal Disorders; Animal Model; Genetic Disorders
Title
Molecular Basis and Clinical Consequences of Iron Disorders
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1024672
Start year
2012
Keywords
Iron Metabolism; Iron Levels; Iron Overload; Anaemia; Cell Biology; Mouse Models; Knockout Mouse; Genetic Disorders