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- Dr Adam Polkinghorne
- Discipline *
- Veterinary Sciences, Microbiology, Biochemistry and Cell Biology
- +61 7 3138 6259
- +61 7 3138 1534
- View location details (QUT staff and student access only)
PhD (Queensland University of Technology)
Research theme: Health
Research discipline: Cell and Molecular Biosciences
- Development of a vaccine for management and control of chlamydial infections in koalas: Chlamydial infection and disease are contributing to a significant decline in the wild koala population in mainland Australia. In collaboration with Australia Zoo and other partners, we are in the process of developing and testing a vaccine, which could be used to prevent the spread of this disease.
- Molecular evolution of Chlamydia pecorum infections in animals, including the koala: Chlamydia pecorum is a bacterial pathogen of sheep and cattle. Our group has previously shown that C.pecorum infections in koalas may have originated from sheep and cattle brought to Australia. With the recent advent of genome sequencing, we plan to investigate the evolution of this bacterial species in Australia.
- Molecular characterisation of Chlamydia-related epitheliocystis agents in wild and cultured fish species: Epitheliocystis is a skink and gill disease of wild and cultured fish species and has long been suspected to be caused by Chlamydia-like organisms. Advances in molecular diagnostics have recently confirmed this link and we are interested in using molecular methods to identify and characterise causative agents of this disease.
- Schmidt-Posthaus H, Polkinghorne AM, Nufer L, Schifferli A, Zimmermann DR, Segner H, Steiner P, Vaughan L, (2012) A natural freshwater origin for two chlamydial species, Candidatus Piscichlamydia salmonis and Candidatus Clavochlamydia salmonicola, causing mixed infections in wild brown trout (Salmo trutta), Environmental Microbiology p2048-2057
- Wan C, Loader J, Hanger J, Beagley K, Timms P, Polkinghorne A, (2011) Using quantitative polymerase chain reaction to correlate Chlamydia pecorum infectious load with ocular, urinary and reproductive tract disease in the koala (Phascolarctos cinereus), Australian Veterinary Journal p409-412
- Marsh JW, Kollipara A, Timms P, Polkinghorne AM, (2011) Novel molecular markers of Chlamydia pecorum genetic diversity in the koala (Phascolarctos cinereus), BMC Microbiology p1-15
- Polkinghorne AM, Schmidt-Posthaus H, Meijer A, Lehner A, Vaughan L, (2010) Novel Chlamydiales associated with epitheliocystis in a leopard shark triakis semifasciata, Diseases of Aquatic Organisms p75-81
- Bertelli C, Collyn F, Croxatto A, Ruckert C, Polkinghorne AM, Kebbi-Beghdadi C, Goesmann A, Vaughan L, Greub G, (2010) The waddlia genome: A window into chlamydial biology, PLoS ONE p1-10
- Polkinghorne AM, Borel N, Becker A, Lu ZH, Zimmerman DR, Brugnera E, Pospischil A, Vaughan L, (2009) Molecular evidence for chlamydial infections in the eyes of sheep, Veterinary Microbiology p142-146
- Polkinghorne AM, Ziegler U, Gonzalez-Hernandez Y, Pospischil A, Timms P, Vaughan L, (2008) Chlamydophila pneumoniae HflX belongs to an uncharacterized family of conserved GTPases and associates with the Escherichia coli 50S large ribosomal subunit, Microbiology p3537-3546
- Polkinghorne A, Hogan R, Vaughan L, Summersgill JT, Timms P, (2006) Differential Expression of Chlamydial Signal Transduction Genes in Normal and Interferon Gamma-induced Persistent Chlamydophila Pneumoniae Infections, Microbes and Infection: a journal on infectious agents and host defenses p61-72
- Devereaux LN, Polkinghorne A, Meijer A, Timms P, (2003) Molecular Evidence for Novel Chlamydial Infections in the Koala (Phascolarctos Cinereus), Systematic and Applied Microbiology p245-253
For more publications by this staff member, visit QUT ePrints, the University's research repository.