This person does not currently hold a position at QUT.

Personal

Name
Dr Eliza Whiteside
Discipline *
Biochemistry and Cell Biology, Medical Physiology, Medical Biotechnology
Phone
+61 7 3138 6112
Fax
+61 7 3138 1534
Email
Location
View location details (QUT staff and student access only)
Identifiers and profiles
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Qualifications

PhD (Queensland University of Technology), Phd (Queensland University of Technology)

Professional memberships
and associations

Australian Society for Medical Research Women in Technology National Breast Cancer Foundation Ambassador

Keywords

Breast cancer, Ghrelin, Growth factors, Hormone receptors, Hormones, Menopause, Non-coding RNA

* Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008

Biography

Research: Cancer Research Program, Institute of Health and Biomedical Innovation Reproductive hormones and breast cancer development project:  The incidence of breast cancer diagnoses is highest in peri and post-menopausal women.  The menopausal transition is characterised by major changes in reproductive hormone levels. Our research group investigates the effects of this altered hormonal milieu on breast cell biology, particularly in the stimulation of tumourigenesis and subsequent breast cancer development. Biomarker discovery and validation: As a collaborator in the Pink Women’s Wellness Program, our research group utilises genomic and proteomic approaches to measure novel and established biomarkers in biological fluids. Our intention is to identify biomarkers that can predict the efficacy of lifestyle interventions for women who are suffering exacerbated menopausal symptoms as a consequence of breast cancer treatment.

 

Areas of research expertise:

  • In vitro models of breast epithelial and breast cancer cell culture
  • Molecular biology
  • Reproductive hormones
  • Medical biotechnology
Publications:
1. Whiteside EJ, Seim I, Pauli J, Walpole C, O’Keeffe AJ, Thomas PB, Carter SL, Josh P, Herington AC, Chopin LK. 2013 Identification of a long non-coding RNA gene, GHSROS (growth hormone secretagogue receptor opposite strand), which stimulates cell migration in non-small cell lung cancer cell lines.  International Journal of Oncology 43(2):566-74.
2. Seim I, Jeffery PL, De Amorim L, Walpole CM, Fung J, Whiteside EJ,Lourie R, Herington AC, Chopin LK. 2013 Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin. Reproductive Biology and Endocrinology 11(1):70.
3. Seim I, Lubik AL, Lehman M, Tomlinson N, Whiteside EJ, Herington A, Nelson C, and Chopin LK. Cloning of a novel insulin-regulated ghrelin transcript in prostate cancer. J Mol Endocrinol, published online on 24 December 2012.
4. Chopin, LK, Walpole C, Seim I, Cunningham P, Murray R, Whiteside EJ, Josh P, Herington AC. Ghrelin and cancer. Mol Cell Endo. 2011 June; 340(1):65-69.
5. Whiteside EJ, Boucaut KJ, Teh A, Garcia-Aragon J, Harvey MB, Herington AC. Elevated concentration of TNF-alpha induces trophoblast differentiation in mouse blastocyst outgrowths. Cell Tissue Res. 2003 Nov; 314(2):275-80.
6. Whiteside EJ, Kan M, Jackson MM, Thompson JG, McNaughton C, Herington AC, Harvey MB. Urokinase-type plasminogen activator (uPA) and matrix metalloproteinase-9(MMP-9) expression and activity during early embryo development in the cow. Anat Embryol. 2001 Dec; 204(6):477-83.
7. Whiteside EJ, Jackson MM, Herington AC, Edwards DR, Harvey MB. Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-3 are key regulators of extracellular matrix degradation by mouse embryos. Biol Reprod. 2001 May; 64(5):1331-7.
8. Pantaleon M, Whiteside EJ, Harvey MB, Barnard RT, Waters MJ, Kaye PL. Functional growth hormone (GH) receptors and GH are expressed by preimplantation mouse embryos: a role for GH in early embryogenesis? Proc Natl Acad Sci U S A. 1997 May 13; 94(10):5125-30.
Grants awarded:
1. Sep 2012 IHBI Human Health and Wellbeing Collaborative Grant Scheme: Dr Charrlotte Seib, Dr Eliza Whiteside, Prof Debra Anderson mentor, A/Prof Lisa Chopin mentor, Professor Kathryn Lee & Prof Janice Humphreys (UCSF, USA)  International collaboration on impact of life stressors on quality of life and telomere length in midlife and older women, $27,800 (12 months).
2. Jun 2012 IHBI ECR Donor Grant: Dr Eliza Whiteside, Follicle-stimulating hormone receptor variants in breast cancer, $10,000 (12 months).
3. Dec 2011 IHBI CT and HHWB Interdomain Grant: Professor Debra Anderson, Dr Eliza Whiteside and other CIs, Investigating biomarkers associated with changes in diet, physical activity and sleep in women with side-effects from breast cancer treatment’, $15,000 (7 months).
4. Feb 2011 QUT ECARD Grant, Dr Eliza Whiteside, The role of follicle-stimulating hormone in breast cancer, $15,000 (12 months).
5. Jan 2011 NHMRC Project Grant (A/Prof Lisa Chopin, CIA and other CIs; Dr Eliza Whiteside, AI), The function of the natural antisense ghrelin receptor gene (GHSROS) in cancer, $476 009 (3 years), ID 1002255.
6. Jan 2001 NHMRC Project Grant (Prof Adrian Herington, CIA and Dr Eliza Whiteside, CIB), The functional roles of ADAM-10 and ADAM-17 (TACE) in the regulation of embryo implantation, $211,000 (2 years), ID138720.

Teaching: School of Biomedical Sciences Bachelor of Biomedical Science, CMB Academic Champion Unit coordinator:

  • LQB184 Biomedical Skills 1
  • LSN101 Molecular Bioscience (Masters in Biotechnology by Coursework)

Areas of teaching expertise (all year levels, Bachelor of  Biomedical Science, Bachelor of Applied Science, Bachelor of Health Science and Bachelor of Nursing/Paramedic Science):

  • Cell and molecular biology
  • Medical biotechnology
  • Reproductive biology
  • Pathophysiology
  • Designing innovative and technology-supported activities for the collaborative learning spaces
  • Supporting students through the First Year Experience
  • Supporting ESL and mature-age students

Community engagement:

  • CSIRO Scientists in School
  • National Breast Cancer Foundation Ambassador
This information has been contributed by Dr Eliza Whiteside.

Teaching

Bachelor of Biomedical Science Cell and Molecular Biology Academic Champion                                     Unit Coordinator:

  • LQB184 Biomedical Skills 1
  • LSN101 Molecular Bioscience (Masters in Biotechnology by Coursework)

Lecturer:

  • Bachelor of Biomedical Science
  • Bachelor of Nursing/Paramedic Science
  • Bachelor of Health
  • Bachelor of Applied Science

Areas of teaching expertise:

  • Cell and molecular biology
  • Medical biotechnology
  • Reproductive biology
  • Pathophysiology
  • Designing innovative and technology-supported activities for the collaborative learning spaces
  • Supporting students through the First Year Experience
  • Supporting ESL and mature-age students
This information has been contributed by Dr Eliza Whiteside.

Experience

2009 – present Lecturer, Queensland University of Technology

2007 – 2008 Lecturer, University of Bedfordshire (UK)

2006 Associate Lecturer, Queensland University of Technology

2003 – 2004 Post-doctoral research fellow, Queensland University of Technology

2001 – 2003 Post-doctoral research fellow, University of Sydney and Royal North Shore Hospital

This information has been contributed by Dr Eliza Whiteside.

Publications

For publications by this staff member, visit QUT ePrints, the University's research repository.