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Associate Professor Jonathan Harris

Faculty of Health,
School - Biomedical Sciences

Personal

Name
Associate Professor Jonathan Harris
Position(s)
Associate Professor in Protein Biochemistry
Faculty of Health,
School - Biomedical Sciences
IHBI Membership
Institute of Health Biomedical Innovation (IHBI),
IHBI Health Projects,
IHBI Biomedical Sciences - CDA
Discipline *
Biochemistry and Cell Biology
Phone
+61 7 3138 6186
Fax
+61 7 3138 6030
Email
Location
View location details (QUT staff and student access only)
Qualifications

PhD in Biochemistry (University of Queensland)

Keywords

Drug design, Molecular modelling, Protein chemistry

* Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008

Biography

Research theme: Health

Research discipline: Cell and Molecular Biosciences

Research areas

Alternative Androgen Blockade: The dominant strategy in chemotherapy for prostate cancer is to prevent testosterone from reaching the prostate tumour and stimulating its growth, a scheme known as androgen blockade. Testosterone is the dominant male hormone; consequently removing it has a range of undesirable side effects. Our research is directed at providing a complementary approach to androgen blockade without the side effects.

Prevention of prostate cancer metastasis: Previous work in the hormone dependent cancer research program has identified the protease KLK4 as a potential target in preventing metastasis of prostate cancer cells. Accordingly we have developed inhibitors to this enzyme and these are being tested on prostate tumour cells growing in test tube conditions to gauge their effects on metastatic behaviour.

Enhancing hormone action: The hormone Ghrelin has a potential therapeutic role in treatment of eating disorders. We have designed and synthesised a novel form of the hormone with enhanced stability and increased potency when tested on cells grown under experimental conditions.

This information has been contributed by Associate Professor Jonathan Harris.

Teaching

Teaching discipline: Cell and Molecular Biosciences

This information has been contributed by Associate Professor Jonathan Harris.

Publications


For more publications by this staff member, visit QUT ePrints, the University's research repository.

Supervision