Professor Kathryn Fairfull-Smith
Faculty of Science,
School of Chemistry & Physics
Biography
Research Discipline : Chemistry Areas of Expertise- Organic Synthesis
- Free Radical Chemistry
- Medicinal Chemistry
- Materials Chemistry
- Materials for Extreme Environments
- Anti-biofilm therapeutics and coatings
- Fluorescent probes
- Anti-hypertensives
- Photosensitive alkoxyamines for NMP2
- Nano sensors for drug delivery and imaging
- 2021 ARC Discovery Project Grant (DP210101317) $453,000
- 2016 Asian Office of Aerospace Research and Development Grant $70,000
- 2015 Asian Office of Aerospace Research and Development Grant $62,000
- 2014 ARC Discovery Project Grant (DP150100234) $447,360
- 2014 ARC Future Fellowship (FT140100746) $771,004
- 2014 Deutsche Forschungsgemeinschaft (DFG) $307,800
- 2014 ATN-DAAD Joint Research Co-operation Scheme $24,600
- 2021-present - Associate Dean Research, Faculty of Science
- 2020-present – Co-Director QUT Centre for Materials Science
- 2020-present – Prof. at Queensland University of Technology
- 2015-present – ARC Future Fellow and A/Prof. at Queensland University of Technology
- 2014-2015 – ARC Future Fellow and Senior Lecturer, Queensland University of Technology
- 2012-2014 – Senior Lecturer at Queensland University of Technology
- 2009-2012 – Vice-Chancellor's Research Fellow at Queensland University of Technology
- 2006-2009 – Postdoctoral research at Queensland University of Technology
- 2004-2006 – Postdoctoral research at the University of Sheffield
- 2001-2004 – PhD in Chemistry at Griffith University
- 1997-2000 – B. Science with 1st Class Honours at Griffith University
Personal details
Positions
- Professor
Faculty of Science,
School of Chemistry & Physics
Research field
Organic Chemistry, Macromolecular and Materials Chemistry, Medicinal and Biomolecular Chemistry
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008
Qualifications
- Doctor of Philosophy (Griffith University)
Professional memberships and associations
MRACI CChem, MRSC
Publications
- Larin, A., Pfrunder, M., Mullen, K., Wiedbrauk, S., Boase, N. & Fairfull-Smith, K. (2023). Synergistic or antagonistic antioxidant combinations - a case study exploring flavonoid-nitroxide hybrids. Organic & Biomolecular Chemistry, 21(8), 1780–1792. https://eprints.qut.edu.au/238038
- Boase, N., Michalek, L., Hooker, J. & Fairfull-Smith, K. (2022). A Versatile Light-Triggered Radical-Releasing Surface Coating Technology. Advanced Materials Technologies, 7(4). https://eprints.qut.edu.au/230066
- Fairfull-Smith, K., Verderosa, A., Hawas, S., Harris, J. & Totsika, M. (2022). Isothiazolone–Nitroxide Hybrids with Activity against Antibiotic-Resistant Staphylococcus aureus Biofilms. ACS Omega, 7(6), 5300–5310. https://eprints.qut.edu.au/229639
- Ndukwe, A., Wiedbrauk, S., Boase, N. & Fairfull-Smith, K. (2022). Strategies to Improve the Potency of Oxazolidinones towards Bacterial Biofilms. Chemistry - An Asian Journal, 17(11). https://eprints.qut.edu.au/230365
- Hansen, K., Chambers, L., Eing, M., Barner-Kowollik, C., Fairfull-Smith, K. & Blinco, J. (2020). A methoxyamine-protecting group for organic radical battery materials: An alternative approach. ChemSusChem, 13(9), 2386–2393. https://eprints.qut.edu.au/199919
- Verderosa, A., Dhouib, R., Fairfull-Smith, K. & Totsika, M. (2020). Nitroxide functionalized antibiotics are promising eradication agents against Staphylococcus aureus biofilms. Antimicrobial Agents and Chemotherapy, 64(1), 1–13. https://eprints.qut.edu.au/197197
- Lussini, V., Blinco, J., Fairfull-Smith, K., Bottle, S. & Colwell, J. (2020). Profluorescent nitroxide sensors for monitoring the natural aging of polymer materials. Polymer Degradation and Stability, 174.
- Verderosa, A., Totsika, M. & Fairfull-Smith, K. (2019). Bacterial biofilm eradication agents: A current review. Frontiers in Chemistry, 7, 1–17. https://eprints.qut.edu.au/197210
- Woehlk, H., Trimble, M., Mansour, S., Pletzer, D., Trouillet, V., Welle, A., Barner, L., Hancock, R., Barner-Kowollik, C. & Fairfull-Smith, K. (2019). Controlling biofilm formation with nitroxide functional surfaces. Polymer Chemistry, 10(31), 4252–4258. https://eprints.qut.edu.au/132180
- Verderosa, A., Harris, J., Dhouib, R., Totsika, M. & Fairfull-Smith, K. (2019). Eradicating uropathogenic Escherichia coli biofilms with a ciprofloxacin-dinitroxide conjugate. MedChemComm, 10(5), 699–711. https://eprints.qut.edu.au/128614
QUT ePrints
For more publications by Kathryn, explore their research in QUT ePrints (our digital repository).
Awards
- Type
- Academic Honours, Prestigious Awards or Prizes
- Reference year
- 2017
- Details
- QUT Vice-Chancellor's Award for Excellence in Research
- Type
- Recipient of a Nationally Competitive Research Fellowship
- Reference year
- 2014
- Details
- ARC Future Fellowship - Fighting slime with free radicals
Selected research projects
- Title
- Eradicating Bacterial Biofilms with Nitroxide-Antimicrobial Hybrids
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- DP210101317
- Start year
- 2021
- Keywords
- DP210101317
- Title
- Fighting Slime with Free Radicals - New Surface Coatings for Biofilm Remediation
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- FT140100746
- Start year
- 2015
- Keywords
- Radicals; Functionalised Surfaces; Biofilms
- Title
- Nitroxide-containing scaffolds for controlling biofilm-related infections
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- DP150100234
- Start year
- 2015
- Keywords
- nitroxide; microparticle; surface coating
- Title
- ARC Centre of Excellence: Free Radical Chemistry and Biotechnology
- Primary fund type
- CAT 1 - Australian Competitive Grant
- Project ID
- CE0561607
- Start year
- 2005
- Keywords
- Free Radical; Flourescence; Antioxidant; Polymer Degradation; Disease; Oxidation; Reactive Oxygen Species; Oxidative Stress; Ataxia Telangiectasia; Chemiluminescence; Stabilisers; Nitroxide
Projects listed above are funded by Australian Competitive Grants. Projects funded from other sources are not listed due to confidentiality agreements.
Supervision
Current supervisions
- The electronic and structural properties of extended, disordered, 2D conjugated polymers synthesized on-surface
PhD, Associate Supervisor
Other supervisors: Professor Jennifer MacLeod - Radiation activated drug delivery for in vivo release
PhD, Mentoring Supervisor
Other supervisors: Dr Nathan Boase - Nitroxide Hybridized Redox Active Therapeutic Agents
PhD, Principal Supervisor
Other supervisors: Dr Nathan Boase - Programming polymer function via ring-opening polymerization of peptides
PhD, Associate Supervisor
Other supervisors: Associate Professor Hendrik Frisch - Design and synthesis of novel PolQ inhibitors for treatment of cancers
PhD, Principal Supervisor
Other supervisors: Adjunct Associate Professor Emma Bolderson, Adjunct Professor Neha S. Gandhi
Completed supervisions (Doctorate)
- Assembly and Reactions of Carboxylic Acids on Metal-Passivated Silicon (2021)
- Photocycloadditions as Tools for Particle Synthesis (2021)
- Dynamic Covalent Chemistry at the Solution: Surface Interface (2020)
- Nitroxide Functionalised Antibiotics for the Eradication of Bacterial Biofilms (2019)
- Nitroxides at the Interface: Bioinspired Polymer Adhesives for Controlling Biofilm-related Infections (2019)
- Polymeric Nanocarriers for the Visualisation and Quantification of Molecular Release (2019)
- The Synthesis and Evaluation of Polyaromatic Profluorescent Nitroxide Probes for the Detection of Photo-oxidative Polymer Degradation (2019)
- Synthesis of Novel Nitroxide Radical Polymer Materials for Imaging and Energy Storage Applications (2018)
- Photosensitive Alkoxyamines: Synthesis and Photochemical Studies for Potential Application in Nitroxide-Mediated Photopolymerization (2017)
- Novel Dual-Acting Nitroxide-Based Hybrid Antioxidants (2016)