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Dr Eloise Dray

Faculty of Health,
School - Biomedical Sciences,
Research - Biomedical Sciences

Personal

Name
Dr Eloise Dray
Position(s)
Research Fellow
Faculty of Health,
School - Biomedical Sciences,
Research - Biomedical Sciences
IHBI Membership
Institute of Health Biomedical Innovation (IHBI),
IHBI Health Projects,
IHBI Biomedical Sciences - CDA
Discipline *
Medical Biochemistry and Metabolomics, Medical Microbiology
Phone
+61 7 3443 7342
Email
Location
View location details (QUT staff and student access only)
Qualifications

PhD (University of Paris-Sud (University of Paris XI))

Keywords

DNA Repair, Homologous Recombination, Breast Cancer, Metastasis, Biochemistry

* Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008

Biography

Current Position. I was recently recruited by the Queensland University of Technology as a Research Fellow, and started my autonomous research group. I am the recipient of a Vice Chancellor Research Fellowship and a National Breast Cancer Foundation Early Career Fellowship. My laboratory is always looking for new talents to enrich the team. Undergraduate students, prospective PhD students and postdoctorate candidates are strongly encouraged to contact me to find out about opportunities available in the lab: eloise.dray@qut.edu.au

Past Positions

2002-2006: PhD training. I received my Ph.D. degree in France, from the University Paris 11 where I studied the tumor suppressor BRCA2 in Arabidopsis thaliana. I applied a combination of genetics, cytology, cell biology, plant physiology and basic biochemistry to succeed in my research. I was able to establish a link between the breast cancer protein BRCA2 and the meiotic recombinase DMC1. This finding opened a totally new path in the international BRCA2-research field, and was published in the EMBO journal.

2006-2011: Postdoctoral training in Patrick Sung’s laboratory at Yale University, USA. During this time, I was extensively trained as a biochemist and rapidly became conversant in recombination protein biochemistry and enzymology. I developed and optimized powerful biochemical tools to analyze new human proteins involved in human disease (PALB2 is involved in breast cancer, pancreas cancer, leukemia and Fanconi anemia) through DNA repair. I deciphered the role of the then poorly understood RAD51AP1 protein. I was able to purify the PALB2 protein (a BRCA2 partner) and study it from a biochemical point of view, establishing its physical interaction with the recombinase RAD51.

Jan. 2012- Jan 2013: Associate Research Fellow “Biology of Triple Negative Breast Cancer” at The University of Queensland, in Melissa Brown’s Laboratory. In 2012, I joined Melissa Brown group at the University of Queensland, Brisbane, Australia, where I acquired new skills in gene expression analysis, and resumed my training in cell-based assays.

This information has been contributed by Dr Eloise Dray.

Teaching

2002-2005: Teaching responsibilities. Total of 300 hours of microbiology (fundamental and applied to industry), genetics, and physiology to a very diverse audience (B.Sc. to Masters students). For this purpose, I designed my own lectures (about 200 hours of lectures and 100 hours of laboratory classes), under the tutelage of senior professors.

This information has been contributed by Dr Eloise Dray.

Publications


Research projects

Grants and projects (Category 1: Australian Competitive Grants only)

Title
Pinpointing critical epigenetic events in triple negative breast cancer
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
ECF-13-04
Start year
2013
Keywords