- Professor Lisa Chopin
Faculty of Health,
School - Biomedical Sciences
- IHBI Membership
Institute of Health Biomedical Innovation (IHBI),
IHBI Health Projects,
IHBI Biomedical Sciences - CDA
- Discipline *
- Biochemistry and Cell Biology, Clinical Sciences, Genetics
- +61 7 3443 7234
- +61 7 3138 1534
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- Identifiers and profiles
PhD (University of Queensland), Masters of Applied Science (Queensland University of Technology), Bachelor of Veterinary Science (hons) (University of Queensland)
- Professional memberships
- Member of Endocrine Society of Australia
- Registered Veterinary surgeon, Veterinary Surgeon´s Board Qld
- Member, Growth hormone research society
Research theme: Health
Research discipline: Medical Sciences
Research program: Hormone Dependent Cancer
The function and signalling mechanisms of ghrelin and the ghrelin-gene derived hormone, obestatin, in prostate, breast, ovarian and colon cancer cell proliferation, metabolism and migration. She has shown that the hormone, ghrelin, and the newly discovered ghrelin derived hormone, obestatin, stimulate cell growth in a range of cancer cell types. By understanding the function and mechanism of action of these hormones in cancer, we may be able to develop new treatments that can slow the growth of these cancers.
The expression and function of ghrelin and ghrelin receptor antisense genes in cancer. Novel genes have recently been discovered that are transcribed from the opposite strand of the ghrelin gene and the ghrelin receptor (GHSR) gene. There is a belief that these novel genes play a role in regulating the ghrelin axis in normal tissues and may promote cell growth in cancer.
Understanding the heterogeneity of breast cancer – a proteomic approach for biomarker discovery and for the discovery of therapeutic targets for the basal-like subtype of breast cancer. Although up to 20% of breast cancers are the basal subtype, this aggressive disease type is generally not recognised in clinical practice. Unlike other breast cancer types, there is no agreed diagnostic method or targeted treatment therapy for this subtype. Therefore, she aims to find new biomarkers and treatments for this disease type.
Areas of expertise
- Breast cancer
- Prostate cancer
- Hormone dependent cancer.
Selected research projects
- The role of the ghrelin axis in breast, ovarian and prostate cancer
- The ghrelin axis in inflammatory bowel disease and colon cancer
- Ghrelin signalling.
Teaching discipline: Medical Sciences
- Life Sciences
For publications by this staff member, visit QUT ePrints, the University's research repository.